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In clinical studies, DoxyPEP has shown promising results in reducing the risk of acquiring syphilis, gonorrhea, and chlamydia by approximately two-thirds when taken within 24 to 72 hours. It's important to note that the current efficacy data is based on research conducted with gay and bisexual cisgender men as well as transgender women. Ongoing research is being conducted for cisgender women, as recommended by the CDC.

The risk of developing antibiotic resistance from a single dose of DoxyPEP is low. As the concern for antibiotic resistance in treating STDs continues to grow, this treatment option proves valuable in preventing the spread of these infections.

It is recommended to take your DoxyPEP tablet within 24 hours, but no later than 72 hours, after engaging in condomless sex. Condomless sex refers to oral, anal, or vaginal intercourse without continuous condom usage, involving skin-to-skin genital contact and/or fluid exchange.

While an STD test is not required for receiving treatment, Shameless Care offers comprehensive STI testing, known for its thoroughness and accuracy. You can explore the available tests here.

DoxyPEP has been found to offer preventive benefits against syphilis, gonorrhea, and chlamydia. It offers no protection whatsoever from viral infections such as HIV, HSV, Hepatitis, etc.

Common side effects of DoxyPEP are typically mild. If you experience stomach upset with antibiotics, taking them with food may alleviate the symptoms. It's important to drink plenty of water when taking doxycycline to avoid esophagitis and to avoid lying down for 30 minutes afterwards. Some individuals may also experience increased sensitivity to the sun while taking doxycycline, so using sunscreen is recommended.

Research indicates DoxyPEP lowers STI risk in women without harming vaginal health. Unlike some antibiotics, doxycycline doesn’t cause Bacterial Vaginosis or yeast infections. For personal medical concerns, consult your Shameless Care physician.

For more information, see our article:

Is DoxyPEP Effective for Cis-Gendered Women?

With Shameless Care, you can maintain a high level of discretion. Here’s how it works:

• Discreet and HIPAA-Compliant: Our system is designed to keep things private. Your medication will arrive in discreet packaging, so no one knows your business but you.
• Prescription Requirements: While we aim for confidentiality, it's important to note that DoxyPEP requires a prescription. This means you need to share your information with a physician—it's a necessary step for any prescription medication.
• No Insurance Needed: One big advantage of using Shameless Care is that we don’t use insurance. Insurance companies compile your medical data from various providers, potentially linking your treatments together. By sidestepping insurance, you can keep your personal choices out of your primary medical chart. Unless you do something like request reimbursement from your insurance provider.
• Treatment for STIs: If you contract gonorrhea, chlamydia, or syphilis, treatment must happen at a traditional medical facility. Unfortunately, diagnoses and treatments there will be recorded on your medical chart. So if you're ultra-concerned about discretion, then DoxyPEP is a better choice than contracting an STI.

Overall, while complete anonymity isn't possible when dealing with prescription meds or STI treatments, Shameless Care offers a more discreet option by eliminating insurance from the equation.

We are now offering a way to get your first dose as soon as possible. We do this by sending a single-dose prescription in advance to your pharmacy in addition to mailing your medication to your home.

All you need to do to take advantage of this is select the option to get one dose in advance on the medical intake form (you'll be redirected to this after checkout) and provide your pharmacy information.

This way, you can protect yourself from any immediate concerns while preparing for next time.

Note: There may be a small fee from your pharmacy to administer one dose.